PDF DatasheetMouse Glucagon receptor Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Glucagon receptor based upon sequence from Mouse
Host: QP6073 protein expressed in E.coli, Yeast..
Tag: GST
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Glucagon receptor, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6073.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Ala27 – Gln143
Amino Acid Sequence: AQVMDFLFEK WKLYSDQCHH NLSLLPPPTE LVCNRTFDKY SCWPDTPPNT TANISCPWYL PWYHKVQHRL VFKRCGPDGQ WVRGPRGQPW RNASQCQLDD EEIEVQKGVA KMYSSQQ
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse Glucagon receptor Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse Glucagon receptor Protein General Information | |
|---|---|
| Alternate Names | |
| GR | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Gcgr |
| Entrez Gene ID | 14527 |
| Ensemble Gene ID | ENSMUSG00000025127 |
| RefSeq Protein Accession(s) | NP_032127.2 |
| RefSeq mRNA Accession(s) | NM_008101.2, XM_017314266.1 |
| UniProt ID(s) | Q61606 |
| UniGene ID(s) | Mm.22329 |
| COSMIC ID Link(s) | Gcgr |
| KEGG Gene ID(s) | mmu:14527 |
| General Description of Recombinant Mouse Glucagon receptor Protein. | |
| G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger syst. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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