PDF DatasheetHuman Growth / differentiation factor 9 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Growth / differentiation factor 9 based upon sequence from Human
Host: QP6076 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Growth/differentiation factor 9, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6076.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Gly320 – Arg454
Amino Acid Sequence: GQETVSSELK KPLGPASFNL SEYFRQFLLP QNECELHDFR LSFSQLKWDN WIVAPHRYNP RYCKGDCPRA VGHRYGSPVH TMVQNIIYEK LDSSVPRPSC VPAKYSPLSV LTIEPDGSIA YKEYEDMIAT KCTCR
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Growth / differentiation factor 9 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Growth / differentiation factor 9 Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | GDF9 |
| Entrez Gene ID | 2661 |
| Ensemble Gene ID | ENSG00000164404 |
| RefSeq Protein Accession(s) | NP_001275753.1 |
| RefSeq mRNA Accession(s) | NM_001288824.2, NM_005260.5, XM_011543308.2 |
| UniProt ID(s) | O60383 |
| UniGene ID(s) | Hs.25022 |
| HGNC ID(s) | HGNC:4224 |
| COSMIC ID Link(s) | GDF9 |
| KEGG Gene ID(s) | hsa:2661 |
| PharmGKB ID(s) | PA28639 |
| General Description of Recombinant Human Growth / differentiation factor 9 Protein. | |
| Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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