PDF DatasheetHuman Glutaredoxin-3 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Glutaredoxin-3 based upon sequence from Human
Host: QP6094 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Glutaredoxin-3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6094.
Bioactivity Data: Untested
Full Length? Full Length
Amino Acid Sequence: AAGAAEAAVA AVEEVGSAGQ FEELLRLKAK SLLVVHFWAP WAPQCAQMNE VMAELAKELP QVSFVKLEAE GVPEVSEKYE ISSVPTFLFF KNSQKIDRLD GAHAPELTKK VQRHASSGSF LPSANEHLKE DLNLRLKKLT HAAPCMLFMK GTPQEPRCGF SKQMVEILHK HNIQFSSFDI FSDEEVRQGL KAYSSWPTYP QLYVSGELIG GLDIIKELEA SEELDTICPK APKLEERLKV LTNKASVMLF MKGNKQEAKC GFSKQILEIL NSTGVEYETF DILEDEEVRQ GLKAYSNWPT YPQLYVKGEL VGGLDIVKEL KENGELLPIL RGEN
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Glutaredoxin-3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Glutaredoxin-3 Protein General Information | |
|---|---|
| Alternate Names | |
| PICOT, GLRX4, TXNL3, GRX4, GRX3, TXNL2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | GLRX3 |
| Entrez Gene ID | 10539 |
| Ensemble Gene ID | ENSG00000108010 |
| RefSeq Protein Accession(s) | NP_001186797.1 |
| RefSeq mRNA Accession(s) | NM_001199868.1, NM_006541.4 |
| UniProt ID(s) | O76003 |
| UniGene ID(s) | Hs.42644 |
| HGNC ID(s) | HGNC:15987 |
| COSMIC ID Link(s) | GLRX3 |
| KEGG Gene ID(s) | hsa:10539 |
| PharmGKB ID(s) | PA162389829 |
| General Description of Recombinant Human Glutaredoxin-3 Protein. | |
| Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator . Crucial regulator of cellular iron homeostasis and hemoglobin maturation. May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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