PDF DatasheetMouse Hyaluronan synthase 2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Hyaluronan synthase 2 based upon sequence from Mouse
Host: QP6144 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Hyaluronan synthase 2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6144.
Bioactivity Data: Untested
Full Length? Cytoplasmic Domain
Expression Region: Glu67 – Leu374
Amino Acid Sequence: EHRKMKKSLE TPIKLNKTVA LCIAAYQEDP DYLRKCLQSV KRLTYPGIKV VMVIDGNSDD DLYMMDIFSE VMGRDKSATY IWKNNFHEKG PGETEESHKE SSQHVTQLVL SNKSICIMQK WGGKREVMYT AFRALGRSVD YVQVCDSDTM LDPASSVEMV KVLEEDPMVG GVGGDVQILN KYDSWISFLS SVRYWMAFNI ERACQSYFGC VQCISGPLGM YRNSLLHEFV EDWYNQEFMG NQCSFGDDRH LTNRVLSLGY ATKYTARSKC LTETPIEYLR WLNQQTRWSK SYFREWLYNA MWFHKHHL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse Hyaluronan synthase 2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse Hyaluronan synthase 2 Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Has2 |
| Entrez Gene ID | 15117 |
| Ensemble Gene ID | ENSMUSG00000022367 |
| RefSeq Protein Accession(s) | NP_032242.3 |
| RefSeq mRNA Accession(s) | NM_008216.3 |
| UniProt ID(s) | P70312 |
| UniGene ID(s) | Mm.5148 |
| COSMIC ID Link(s) | Has2 |
| KEGG Gene ID(s) | mmu:15117 |
| General Description of Recombinant Mouse Hyaluronan synthase 2 Protein. | |
| Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most Extracellular domain matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction and it is particularly responsible for the synthesis of high molecular mass hyaluronan. Required for the transition of endocardial cushion cells into mesenchymal cells, a process crucial for heart development. May also play a role in vasculogenesis. High molecular mass hyaluronan also play a role in early contact inhibition a process which stops cell growth when cells come into contact with each other or the Extracellular domain matrix. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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