PDF DatasheetHuman Histone H3.1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Histone H3.1 based upon sequence from Human
Host: QP6161 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Histone H3.1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6161.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala1 – Ala136
Amino Acid Sequence: ARTKQTARKS TGGKAPRKQL ATKAARKSAP ATGGVKKPHR YRPGTVALRE IRRYQKSTEL LIRKLPFQRL VREIAQDFKT DLRFQSSAVM ALQEACEAYL VGLFEDTNLC AIHAKRVTIM PKDIQLARRI RGERA
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Histone H3.1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Histone H3.1 Protein General Information | |
|---|---|
| Alternate Names | |
| H3/b, H3FB, H3/d, H3.1, H3FD, H3.f, H3/f, H3FF, H3FH, H3/h, H3F1K, H3/k, H3FK, H3/l, H3FL, H3FI, H3/i, H3FJ, H3/j, H3FA, H3/A, H3FC, H3/c | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | HIST1H3D |
| Entrez Gene ID | 8350 |
| Ensemble Gene ID | ENSG00000197409 |
| RefSeq Protein Accession(s) | NP_003520.1 |
| RefSeq mRNA Accession(s) | NM_003529.2, NM_003530.4, NM_003531.2, NM_003532.2, NM_003533.2, NM_003534.2, NM_003535.2, NM_003536.2, NM_003537.3, NM_021018.2 |
| UniProt ID(s) | P68431 |
| UniGene ID(s) | Hs.132854 |
| HGNC ID(s) | HGNC:4766 |
| COSMIC ID Link(s) | HIST1H3D |
| KEGG Gene ID(s) | hsa:8350 |
| PharmGKB ID(s) | PA29148 |
| General Description of Recombinant Human Histone H3.1 Protein. | |
| Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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