PDF DatasheetHuman Holliday junction recognition protein Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Holliday junction recognition protein based upon sequence from Human
Host: QP6162 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Holliday junction recognition protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6162.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Val748
Amino Acid Sequence: MLGTLRAMEG EDVEDDQLLQ KLRASRRRFQ RRMQRLIEKY NQPFEDTPVV QMATLTYETP QGLRIWGGRL IKERNEGEIQ DSSMKPADRT DGSVQAAAWG PELPSHRTVL GADSKSGEVD ATSDQEESVA WALAPAVPQS PLKNELRRKY LTQVDILLQG AEYFECAGNR AGRDVRVTPL PSLASPAVPA PGYCSRISRK SPGDPAKPAS SPREWDPLHP SSTDMALVPR NDSLSLQETS SSSFLSSQPF EDDDICNVTI SDLYAGMLHS MSRLLSTKPS SIISTKTFIM QNWNSRRRHR YKSRMNKTYC KGARRSQRSS KENFIPCSEP VKGTGALRDC KNVLDVSCRK TGLKLEKAFL EVNRPQIHKL DPSWKERKVT PSKYSSLIYF DSSATYNLDE ENRFRTLKWL ISPVKIVSRP TIRQGHGENR QREIEIRFDQ LHREYCLSPR NQPRRMCLPD SWAMNMYRGG PASPGGLQGL ETRRLSLPSS KAKAKSLSEA FENLGKRSLE AGRCLPKSDS SSSLPKTNPT HSATRPQQTS DLHVQGNSSG IFRKSVSPSK TLSVPDKEVP GHGRNRYDEI KEEFDKLHQK YCLKSPGQMT VPLCIGVSTD KASMEVRYQT EGFLGKLNPD PHFQGFQKLP SSPLGCRKSL LGSTAIEAPS STCVARAITR DGTRDHQFPA KRPRLSEPQG SGRQGNSLGA SDGVDNTVRP GDQGSSSQPN SEERGENTSY RMEEKSDFML EKLETKSV
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Holliday junction recognition protein Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Holliday junction recognition protein Protein General Information | |
|---|---|
| Alternate Names | |
| URLC9, hFLEG1, FAKTS | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | HJURP |
| Entrez Gene ID | 55355 |
| Ensemble Gene ID | ENSG00000123485 |
| RefSeq Protein Accession(s) | NP_001269891.1 |
| RefSeq mRNA Accession(s) | NM_001282962.1, NM_001282963.1, NM_018410.4 |
| UniProt ID(s) | Q8NCD3 |
| UniGene ID(s) | Hs.532968 |
| HGNC ID(s) | HGNC:25444 |
| COSMIC ID Link(s) | HJURP |
| KEGG Gene ID(s) | hsa:55355 |
| PharmGKB ID(s) | PA162390937 |
| General Description of Recombinant Human Holliday junction recognition protein Protein. | |
| Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents prature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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