PDF DatasheetHuman Hydroxymethylglutaryl-CoA lyase, mitochondrial Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Hydroxymethylglutaryl-CoA lyase, mitochondrial based upon sequence from Human
Host: QP6168 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Hydroxymethylglutaryl-CoA lyase, mitochondrial, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6168.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Thr1 – Leu325
Amino Acid Sequence: TLPKRVKIVE VGPRDGLQNE KNIVSTPVKI KLIDMLSEAG LSVIETTSFV SPKWVPQMGD HTEVLKGIQK FPGINYPVLT PNLKGFEAAV AAGAKEVVIF GAASELFTKK NINCSIEESF QRFDAILKAA QSANISVRGY VSCALGCPYE GKISPAKVAE VTKKFYSMGC YEISLGDTIG VGTPGIMKDM LSAVMQEVPL AALAVHCHDT YGQALANTLM ALQMGVSVVD SSVAGLGGCP YAQGASGNLA TEDLVYMLEG LGIHTGVNLQ KLLEAGNFIC QALNRKTSSK VAQATCKL
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Hydroxymethylglutaryl-CoA lyase, mitochondrial Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Hydroxymethylglutaryl-CoA lyase, mitochondrial Protein General Information | |
|---|---|
| Alternate Names | |
| HL | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | HMGCL |
| Entrez Gene ID | 3155 |
| Ensemble Gene ID | ENSG00000117305 |
| RefSeq Protein Accession(s) | NP_000182.2 |
| RefSeq mRNA Accession(s) | NM_000191.2, NM_001166059.1 |
| UniProt ID(s) | P35914 |
| UniGene ID(s) | Hs.533444 |
| HGNC ID(s) | HGNC:5005 |
| COSMIC ID Link(s) | HMGCL |
| KEGG Gene ID(s) | hsa:3155 |
| PharmGKB ID(s) | PA29336 |
| General Description of Recombinant Human Hydroxymethylglutaryl-CoA lyase, mitochondrial Protein. | |
| Key enzyme in ketogenesis (ketone body formation). Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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