PDF DatasheetHuman HMGCR Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant HMGCR based upon sequence from Human
Host: QP6169 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) HMGCR, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6169.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met588 – Thr887
Amino Acid Sequence: MTRGPVVRLP RACDSAEVKA WLETSEGFAV IKEAFDSTSR FARLQKLHTS IAGRNLYIRF QSRSGDAMGM NMISKGTEKA LSKLHEYFPE MQILAVSGNY CTDKKPAAIN WIEGRGKSVV CEAVIPAKVV REVLKTTTEA MIEVNINKNL VGSAMAGSIG GYNAHAANIV TAIYIACGQD AAQNVGSSNC ITLMEASGPT NEDLYISCTM PSIEIGTVGG GTNLLPQQAC LQMLGVQGAC KDNPGENARQ LARIVCGTVM AGELSLMAAL AAGHLVKSHM IHNRSKINLQ DLQGACTKKT
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human HMGCR Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human HMGCR Protein General Information | |
|---|---|
| Alternate Names | |
| LDLCQ3, 3-hydroxy-3-methylglutaryl-coenzyme A reducta | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | HMGCR |
| Entrez Gene ID | 3156 |
| Ensemble Gene ID | ENSG00000113161 |
| RefSeq Protein Accession(s) | NP_000850.1 |
| RefSeq mRNA Accession(s) | NM_000859.2, NM_001130996.1, XM_011543357.1, XM_011543358.1 |
| UniProt ID(s) | P04035 |
| UniGene ID(s) | Hs.628096 |
| HGNC ID(s) | HGNC:5006 |
| COSMIC ID Link(s) | HMGCR |
| KEGG Gene ID(s) | hsa:3156 |
| PharmGKB ID(s) | PA189 |
| General Description of Recombinant Human HMGCR Protein. | |
| Transmbrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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