PDF DatasheetHuman Heterogeneous nuclear ribonucleoprotein L Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Heterogeneous nuclear ribonucleoprotein L based upon sequence from Human
Host: QP6177 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Heterogeneous nuclear ribonucleoprotein L, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6177.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Ser589
Amino Acid Sequence: MSRRLLPRAE KRRRRLEQRQ QPDEQRRRSG AMVKMAAAGG GGGGGRYYGG GSEGGRAPKR LKTDNAGDQH GGGGGGGGGA GAAGGGGGGE NYDDPHKTPA SPVVHIRGLI DGVVEADLVE ALQEFGPISY VVVMPKKRQA LVEFEDVLGA CNAVNYAADN QIYIAGHPAF VNYSTSQKIS RPGDSDDSRS VNSVLLFTIL NPIYSITTDV LYTICNPCGP VQRIVIFRKN GVQAMVEFDS VQSAQRAKAS LNGADIYSGC CTLKIEYAKP TRLNVFKNDQ DTWDYTNPNL SGQGDPGSNP NKRQRQPPLL GDHPAEYGGP HGGYHSHYHD EGYGPPPPHY EGRRMGPPVG GHRRGPSRYG PQYGHPPPPP PPPEYGPHAD SPVLMVYGLD QSKMNCDRVF NVFCLYGNVE KVKFMKSKPG AAMVEMADGY AVDRAITHLN NNFMFGQKLN VCVSKQPAIM PGQSYGLEDG SCSYKDFSES RNNRFSTPEQ AAKNRIQHPS NVLHFFNAPL EVTEENFFEI CDELGVKRPS SVKVFSGKSE RSSSGLLEWE SKSDALETLG FLNHYQMKNP NGPYPYTLKL CFSTAQHAS
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Heterogeneous nuclear ribonucleoprotein L Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Heterogeneous nuclear ribonucleoprotein L Protein (1-589aa) General Information | |
|---|---|
| Alternate Names | |
| HNRPL, hnRNP-L, P/OKcl.14 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | HNRNPL |
| Entrez Gene ID | 3191 |
| Ensemble Gene ID | ENSG00000104824 |
| RefSeq Protein Accession(s) | NP_001005335.1 |
| RefSeq mRNA Accession(s) | NM_001005335.1, NM_001533.2, XM_011526889.1 |
| UniProt ID(s) | P14866 |
| UniGene ID(s) | Hs.644906 |
| HGNC ID(s) | HGNC:5045 |
| COSMIC ID Link(s) | HNRNPL |
| KEGG Gene ID(s) | hsa:3191 |
| PharmGKB ID(s) | PA162391389 |
| General Description of Recombinant Human Heterogeneous nuclear ribonucleoprotein L Protein (1-589aa). | |
| Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elents. Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts. Associates, together with APEX1, to the negative calcium responsive elent (nCaRE) B2 of the APEX2 promoter. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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