PDF DatasheetHuman Heterogeneous nuclear ribonucleoprotein M Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Heterogeneous nuclear ribonucleoprotein M based upon sequence from Human
Host: QP6178 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Heterogeneous nuclear ribonucleoprotein M, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6178.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala2 – Ala730
Amino Acid Sequence: AAGVEAAAEV AATEIKMEEE SGAPGVPSGN GAPGPKGEGE RPAQNEKRKE KNIKRGGNRF EPYANPTKRY RAFITNIPFD VKWQSLKDLV KEKVGEVTYV ELLMDAEGKS RGCAVVEFKM EESMKKAAEV LNKHSLSGRP LKVKEDPDGE HARRAMQKVM ATTGGMGMGP GGPGMITIPP SILNNPNIPN EIIHALQAGR LGSTVFVANL DYKVGWKKLK EVFSMAGVVV RADILEDKDG KSRGIGTVTF EQSIEAVQAI SMFNGQLLFD RPMHVKMDER ALPKGDFFPP ERPQQLPHGL GGIGMGLGPG GQPIDANHLN KGIGMGNIGP AGMGMEGIGF GINKMGGMEG PFGGGMENMG RFGSGMNMGR INEILSNALK RGEIIAKQGG GGGGGSVPGI ERMGPGIDRL GGAGMERMGA GLGHGMDRVG SEIERMGLVM DRMGSVERMG SGIERMGPLG LDHMASSIER MGQTMERIGS GVERMGAGMG FGLERMAAPI DRVGQTIERM GSGVERMGPA IERMGLSMER MVPAGMGAGL ERMGPVMDRM ATGLERMGAN NLERMGLERM GANSLERMGL ERMGANSLER MGPAMGPALG AGIERMGLAM GGGGGASFDR AIEMERGNFG GSFAGSFGGA GGHAPGVARK ACQIFVRNLP FDFTWKMLKD KFNECGHVLY ADIKMENGKS KGCGVVKFES PEVAERACRM MNGMKLSGRE IDVRIDRNA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Heterogeneous nuclear ribonucleoprotein M Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Heterogeneous nuclear ribonucleoprotein M Protein General Information | |
|---|---|
| Alternate Names | |
| HTGR1, NAGR1, hnRNP M, HNRPM, CEAR, HNRNPM4, HNRPM4 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | HNRNPM |
| Entrez Gene ID | 4670 |
| Ensemble Gene ID | ENSG00000099783 |
| RefSeq Protein Accession(s) | NP_005959.2 |
| RefSeq mRNA Accession(s) | NM_005968.4, NM_031203.3 |
| UniProt ID(s) | P52272 |
| UniGene ID(s) | Hs.465808 |
| HGNC ID(s) | HGNC:5046 |
| COSMIC ID Link(s) | HNRNPM |
| KEGG Gene ID(s) | hsa:4670 |
| PharmGKB ID(s) | PA29370 |
| General Description of Recombinant Human Heterogeneous nuclear ribonucleoprotein M Protein. | |
| Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinobryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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