PDF DatasheetHuman HSD11B1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant HSD11B1 based upon sequence from Human
Host: QP6183 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) HSD11B1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6183.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Glu25 – Lys292
Amino Acid Sequence: EEFRPEMLQG KKVIVTGASK GIGREMAYHL AKMGAHVVVT ARSKETLQKV VSHCLELGAA SAHYIAGTME DMTFAEQFVA QAGKLMGGLD MLILNHITNT SLNLFHDDIH HVRKSMEVNF LSYVVLTVAA LPMLKQSNGS IVVVSSLAGK VAYPMVAAYS ASKFALDGFF SSIRKEYSVS RVNVSITLCV LGLIDTETAM KAVSGIVHMQ AAPKEECALE IIKGGALRQE EVYYDSSLWT TLLIRNPCRK ILEFLYSTSY NMDRFINK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human HSD11B1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human HSD11B1 Protein General Information | |
|---|---|
| Alternate Names | |
| HDL, CORTRD2, 11-beta-HSD1, HSD11B, HSD11, 11-DH, HSD11L, SDR26C1, Corticosteroid 11-beta-dehydrogenase isozyme | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | HSD11B1 |
| Entrez Gene ID | 3290 |
| Ensemble Gene ID | ENSG00000117594 |
| RefSeq Protein Accession(s) | NP_001193670.1 |
| RefSeq mRNA Accession(s) | NM_001206741.1, NM_005525.3, NM_181755.2 |
| UniProt ID(s) | P28845 |
| UniGene ID(s) | Hs.195040 |
| HGNC ID(s) | HGNC:5208 |
| COSMIC ID Link(s) | HSD11B1 |
| KEGG Gene ID(s) | hsa:3290 |
| PharmGKB ID(s) | PA29476 |
| General Description of Recombinant Human HSD11B1 Protein. | |
| Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.