PDF DatasheetHuman HSP90AA1 / HSP90 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant HSP90AA1 / HSP90 based upon sequence from Human
Host: QP6184 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) HSP90AA1 / HSP90, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6184.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Asp9 – Asp232
Amino Acid Sequence: DQPMEEEEVE TFAFQAEIAQ LMSLIINTFY SNKEIFLREL ISNSSDALDK IRYESLTDPS KLDSGKELHI NLIPNKQDRT LTIVDTGIGM TKADLINNLG TIAKSGTKAF MEALQAGADI SMIGQFGVGF YSAYLVAEKV TVITKHNDDE QYAWESSAGG SFTVRTDTGE PMGRGTKVIL HLKEDQTEYL EERRIKEIVK KHSQFIGYPI TLFVEKERDK EVSD
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human HSP90AA1 / HSP90 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human HSP90AA1 / HSP90 Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | HSP90AA1 |
| Entrez Gene ID | 3320 |
| Ensemble Gene ID | ENSG00000080824 |
| RefSeq Protein Accession(s) | NP_001017963.2 |
| RefSeq mRNA Accession(s) | NM_001017963.2, NM_005348.3 |
| UniProt ID(s) | P07900 |
| UniGene ID(s) | Hs.525600 |
| HGNC ID(s) | HGNC:5253 |
| COSMIC ID Link(s) | HSP90AA1 |
| KEGG Gene ID(s) | hsa:3320 |
| PharmGKB ID(s) | PA29519 |
| General Description of Recombinant Human HSP90AA1 / HSP90 Protein. | |
| Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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