PDF DatasheetHuman IFNAR1 / IFNAR Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant IFNAR1 / IFNAR based upon sequence from Human
Host: QP6203 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) IFNAR1 / IFNAR, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6203.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Arg48 – Lys436
Amino Acid Sequence: RWNRSDESVG NVTFSFDYQK TGMDNWIKLS GCQNITSTKC NFSSLKLNVY EEIKLRIRAE KENTSSWYEV DSFTPFRKAQ IGPPEVHLEA EDKAIVIHIS PGTKDSVMWA LDGLSFTYSL VIWKNSSGVE ERIENIYSRH KIYKLSPETT YCLKVKAALL TSWKIGVYSP VHCIKTTVEN ELPPPENIEV SVQNQNYVLK WDYTYANMTF QVQWLHAFLK RNPGNHLYKW KQIPDCENVK TTQCVFPQNV FQKGIYLLRV QASDGNNTSF WSEEIKFDTE IQAFLLPPVF NIRSLSDSFH IYIGAPKQSG NTPVIQDYPL IYEIIFWENT SNAERKIIEK KTDVTVPNLK PLTVYCVKAR AHTMDEKLNK SSVFSDAVCE KTKPGNTSK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human IFNAR1 / IFNAR Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human IFNAR1 / IFNAR Protein General Information | |
|---|---|
| Alternate Names | |
| IFNAR1, IFNAR, IFNAR, AVP, IFRC, IFN-alpha-REC, IFNBR | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IFNAR1 |
| Entrez Gene ID | 3454 |
| Ensemble Gene ID | ENSG00000142166 |
| RefSeq Protein Accession(s) | NP_000620.2 |
| RefSeq mRNA Accession(s) | NM_000629.2, XM_005260964.2 |
| UniProt ID(s) | P17181 |
| UniGene ID(s) | Hs.529400 |
| HGNC ID(s) | HGNC:5432 |
| COSMIC ID Link(s) | IFNAR1 |
| KEGG Gene ID(s) | hsa:3454 |
| PharmGKB ID(s) | PA29670 |
| General Description of Recombinant Human IFNAR1 / IFNAR Protein. | |
| Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits thselves. Can also transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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