PDF DatasheetHuman Indolethylamine N-methyltransferase Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Indolethylamine N-methyltransferase based upon sequence from Human
Host: QP6233 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Indolethylamine N-methyltransferase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6233.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Pro263
Amino Acid Sequence: MKGGFTGGDE YQKHFLPRDY LATYYSFDGS PSPEAEMLKF NLECLHKTFG PGGLQGDTLI DIGSGPTIYQ VLAACDSFQD ITLSDFTDRN REELEKWLKK EPGAYDWTPA VKFACELEGN SGRWEEKEEK LRAAVKRVLK CDVHLGNPLA PAVLPLADCV LTLLAMECAC CSLDAYRAAL CNLASLLKPG GHLVTTVTLR LPSYMVGKRE FSCVALEKEE VEQAVLDAGF DIEQLLHSPQ SYSVTNAANN GVCFIVARKK PGP
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Indolethylamine N-methyltransferase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Indolethylamine N-methyltransferase Protein General Information | |
|---|---|
| Alternate Names | |
| TEMT | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | INMT |
| Entrez Gene ID | 11185 |
| Ensemble Gene ID | ENSG00000241644 |
| RefSeq Protein Accession(s) | NP_001186148.1 |
| RefSeq mRNA Accession(s) | NM_001199219.1, NM_006774.4 |
| UniProt ID(s) | O95050 |
| UniGene ID(s) | Hs.632629 |
| HGNC ID(s) | HGNC:6069 |
| COSMIC ID Link(s) | INMT |
| KEGG Gene ID(s) | hsa:11185 |
| PharmGKB ID(s) | PA403 |
| General Description of Recombinant Human Indolethylamine N-methyltransferase Protein. | |
| Functions as thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide. Plays an important role in the detoxification of selenium compounds . Catalyzes the N-methylation of tryptamine and structurally related compounds.1 Publication | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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