PDF DatasheetMouse Interferon regulatory factor 8 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Interferon regulatory factor 8 based upon sequence from Mouse
Host: QP6235 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Interferon regulatory factor 8, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6235.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Val424
Amino Acid Sequence: MCDRNGGRRL RQWLIEQIDS SMYPGLIWEN DEKTMFRIPW KHAGKQDYNQ EVDASIFKAW AVFKGKFKEG DKAEPATWKT RLRCALNKSP DFEEVTDRSQ LDISEPYKVY RIVPEEEQKC KLGVAPAGCM SEVPEMECGR SEIEELIKEP SVDEYMGMTK RSPSPPEACR SQILPDWWVQ QPSAGLPLVT GYAAYDTHHS AFSQMVISFY YGGKLVGQAT TTCLEGCRLS LSQPGLPKLY GPDGLEPVCF PTADTIPSER QRQVTRKLFG HLERGVLLHS NRKGVFVKRL CQGRVFCSGN AVVCKGRPNK LERDEVVQVF DTNQFIRELQ QFYATQSRLP DSRVVLCFGE EFPDTVPLRS KLILVQVEQL YARQLVEEAG KSCGAGSLMP ALEEPQPDQA FRMFPDICTS HQRPFFRENQ QITV
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse Interferon regulatory factor 8 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse Interferon regulatory factor 8 Protein General Information | |
|---|---|
| Alternate Names | |
| AI893568, ICSBP, IRF-8, Icsbp1, Myls | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Irf8 |
| Entrez Gene ID | 15900 |
| Ensemble Gene ID | ENSMUSG00000041515 |
| RefSeq Protein Accession(s) | NP_001288740.1 |
| RefSeq mRNA Accession(s) | NM_001301811.1, NM_008320.4 |
| UniProt ID(s) | P23611 |
| UniGene ID(s) | Mm.334861 |
| COSMIC ID Link(s) | Irf8 |
| KEGG Gene ID(s) | mmu:15900 |
| General Description of Recombinant Mouse Interferon regulatory factor 8 Protein. | |
| Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a regulatory role in cells of the immune syst. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5′-TGAnTCA/GAAA-3′), an immune-specific regulatory elent, followed by cooperative binding of BATF and IRF8 and activation of genes. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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