PDF DatasheetHuman Immunity-related GTPase family M protein Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Immunity-related GTPase family M protein based upon sequence from Human
Host: QP6236 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Immunity-related GTPase family M protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6236.
Bioactivity Data: Untested
Full Length? Full Length
Amino Acid Sequence: MEAMNVEKAS ADGNLPEVIS NIKETLKIVS RTPVNITMAG DSGNGMSTFI SALRNTGHEG KASPPTELVK ATQRCASYFS SHFSNVVLWD LPGTGSATTT LENYLMEMQF NRYDFIMVAS AQFSMNHVML AKTAEDMGKK FYIVWTKLDM DLSTGALPEV QLLQIRENVL ENLQKERVCE Y
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Immunity-related GTPase family M protein Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Immunity-related GTPase family M protein Protein General Information | |
|---|---|
| Alternate Names | |
| LRG47, IRGM1, LRG-47, IFI1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IRGM |
| Entrez Gene ID | 345611 |
| Ensemble Gene ID | ENSG00000237693 |
| RefSeq Protein Accession(s) | NP_001139277.1 |
| RefSeq mRNA Accession(s) | NM_001145805.1 |
| UniProt ID(s) | A1A4Y4 |
| UniGene ID(s) | Hs.519680 |
| HGNC ID(s) | HGNC:29597 |
| COSMIC ID Link(s) | IRGM |
| KEGG Gene ID(s) | hsa:345611 |
| PharmGKB ID(s) | PA142671652 |
| General Description of Recombinant Human Immunity-related GTPase family M protein Protein. | |
| Putative GTPase which is required for clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. May also play a role in macrophages adhesion and motility | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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