PDF DatasheetHuman Integrin alpha-2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Integrin alpha-2 based upon sequence from Human
Host: QP6238 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Integrin alpha-2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6238.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Trp188 – Glu365
Amino Acid Sequence: WDAVKNFLEK FVQGLDIGPT KTQVGLIQYA NNPRVVFNLN TYKTKEEMIV ATSQTSQYGG DLTNTFGAIQ YARKYAYSAA SGGRRSATKV MVVVTDGESH DGSMLKAVID QCNHDNILRF GIAVLGYLNR NALDTKNLIK EIKAIASIPT ERYFFNVSDE AALLEKAGTL GEQIFSIE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Integrin alpha-2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Integrin alpha-2 Protein General Information | |
|---|---|
| Alternate Names | |
| HPA-5, VLA-2, VLAA2, CD49B, BR, GPIa | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ITGA2 |
| Entrez Gene ID | 3673 |
| Ensemble Gene ID | ENSG00000164171 |
| RefSeq Protein Accession(s) | NP_002194.2 |
| RefSeq mRNA Accession(s) | NM_002203.3 |
| UniProt ID(s) | P17301 |
| UniGene ID(s) | Hs.482077 |
| HGNC ID(s) | HGNC:6137 |
| COSMIC ID Link(s) | ITGA2 |
| KEGG Gene ID(s) | hsa:3673 |
| PharmGKB ID(s) | PA204 |
| General Description of Recombinant Human Integrin alpha-2 Protein. | |
| Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized Extracellular domain matrix. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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