PDF DatasheetMouse Integrin alpha-L Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Integrin alpha-L based upon sequence from Mouse
Host: QP6240 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Integrin alpha-L, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6240.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Asp153 – Leu325
Amino Acid Sequence: DLVFLFDGSQ SLDRKDFEKI LEFMKDVMRK LSNTSYQFAA VQFSTDCRTE FTFLDYVKQN KNPDVLLGSV QPMFLLTNTF RAINYVVAHV FKEESGARPD ATKVLVIITD GEASDKGNIS AAHDITRYII GIGKHFVSVQ KQKTLHIFAS EPVEEFVKIL DTFEKLKDLF TDL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse Integrin alpha-L Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse Integrin alpha-L Protein General Information | |
|---|---|
| Alternate Names | |
| LFA-1, Ly-21, Ly-15, Cd11a, LFA-1A, (p180) | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Itgal |
| Ensemble Gene ID | ENSMUSG00000030830 |
| UniProt ID(s) | P24063 |
| UniGene ID(s) | Mm.1618 |
| COSMIC ID Link(s) | Itgal |
| General Description of Recombinant Mouse Integrin alpha-L Protein. | |
| Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Mice expressing a null mutation of the alpha-L subunit gene donstrate impaired tumor rejection and impaired leukocytes recruitment. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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