PDF DatasheetHuman Tyrosine-protein kinase JAK1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Tyrosine-protein kinase JAK1 based upon sequence from Human
Host: QP6244 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Tyrosine-protein kinase JAK1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6244.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Glu850 – Lys1154
Amino Acid Sequence: EQNPDIVSEK KPATEVDPTH FEKRFLKRIR DLGEGHFGKV ELCRYDPEGD NTGEQVAVKS LKPESGGNHI ADLKKEIEIL RNLYHENIVK YKGICTEDGG NGIKLIMEFL PSGSLKEYLP KNKNKINLKQ QLKYAVQICK GMDYLGSRQY VHRDLAARNV LVESEHQVKI GDFGLTKAIE TDKEYYTVKD DRDSPVFWYA PECLMQSKFY IASDVWSFGV TLHELLTYCD SDSSPMALFL KMIGPTHGQM TVTRLVNTLK EGKRLPCPPN CPDEVYQLMR KCWEFQPSNR TSFQNLIEGF EALLK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Tyrosine-protein kinase JAK1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Tyrosine-protein kinase JAK1 Protein General Information | |
|---|---|
| Alternate Names | |
| JTK3, JAK1B, JAK1A | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | JAK1 |
| Entrez Gene ID | 3716 |
| Ensemble Gene ID | ENSG00000162434 |
| RefSeq Protein Accession(s) | NP_001307852.1 |
| RefSeq mRNA Accession(s) | NM_001320923.1, NM_001321852.1, NM_001321853.1, NM_001321854.1, NM_001321855.1, NM_001321856.1, NM_002227.3 |
| UniProt ID(s) | P23458 |
| UniGene ID(s) | Hs.207538 |
| HGNC ID(s) | HGNC:6190 |
| COSMIC ID Link(s) | JAK1 |
| KEGG Gene ID(s) | hsa:3716 |
| PharmGKB ID(s) | PA29988 |
| General Description of Recombinant Human Tyrosine-protein kinase JAK1 Protein. | |
| Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor. ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. |
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Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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