PDF DatasheetHuman KLK7 / PRSS6 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant KLK7 / PRSS6 based upon sequence from Human
Host: QP6267 protein expressed in E.coli, Yeast..
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) KLK7 / PRSS6, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6267.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Asp28 – Arg253
Amino Acid Sequence: DKIIDGAPCA RGSHPWQVAL LSGNQLHCGG VLVNERWVLT AAHCKMNEYT VHLGSDTLGD RRAQRIKASK SFRHPGYSTQ THVNDLMLVK LNSQARLSSM VKKVRLPSRC EPPGTTCTVS GWGTTTSPDV TFPSDLMCVD VKLISPQDCT KVYKDLLENS MLCAGIPDSK KNACNGDSGG PLVCRGTLQG LVSWGTFPCG QPNDPGVYTQ VCKFTKWIND TMKKHR
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human KLK7 / PRSS6 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human KLK7 / PRSS6 Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | KLK7 |
| Entrez Gene ID | 5650 |
| Ensemble Gene ID | ENSG00000169035 |
| RefSeq Protein Accession(s) | NP_001193982.1 |
| RefSeq mRNA Accession(s) | NM_001207053.1, NM_001243126.1, NM_005046.3, NM_139277.2 |
| UniProt ID(s) | P49862 |
| UniGene ID(s) | Hs.151254 |
| HGNC ID(s) | HGNC:6368 |
| COSMIC ID Link(s) | KLK7 |
| KEGG Gene ID(s) | hsa:5650 |
| PharmGKB ID(s) | PA30157 |
| General Description of Recombinant Human KLK7 / PRSS6 Protein. | |
| May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at ’14-Tyr-|-Gln-15′ and insulin B chain at ‘6-Leu-|-Cys-7′, ’16-Tyr-|-Leu-17′, ’25-Phe-|-Tyr-26′ and ’26-Tyr-|-Thr-27’. Could play a role in the activation of precursors to inflammatory cytokines. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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