PDF DatasheetMouse Legumain / LGMN Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Legumain / LGMN based upon sequence from Mouse
Host: QP6302 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Legumain/ LGMN, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6302.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Val18 – Asn325
Amino Acid Sequence: VPVGVDDPED GGKHWVVIVA GSNGWYNYRH QADACHAYQI IHRNGIPDEQ IIVMMYDDIA NSEENPTPGV VINRPNGTDV YKGVLKDYTG EDVTPENFLA VLRGDAEAVK GKGSGKVLKS GPRDHVFIYF TDHGATGILV FPNDDLHVKD LNKTIRYMYE HKMYQKMVFY IEACESGSMM NHLPDDINVY ATTAANPKES SYACYYDEER GTYLGDWYSV NWMEDSDVED LTKETLHKQY HLVKSHTNTS HVMQYGNKSI STMKVMQFQG MKHRASSPIS LPPVTHLDLT PSPDVPLTIL KRKLLRTN
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse Legumain / LGMN Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse Legumain / LGMN Protein General Information | |
|---|---|
| Alternate Names | |
| Legumain/ LGMN, AI746452, Prsc1, AU022324, AEP | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Lgmn |
| Entrez Gene ID | 19141 |
| Ensemble Gene ID | ENSMUSG00000021190 |
| RefSeq Protein Accession(s) | NP_035305.1 |
| RefSeq mRNA Accession(s) | NM_011175.3 |
| UniProt ID(s) | O89017 |
| UniGene ID(s) | Mm.17185 |
| COSMIC ID Link(s) | Lgmn |
| KEGG Gene ID(s) | mmu:19141 |
| General Description of Recombinant Mouse Legumain / LGMN Protein. | |
| Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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