PDF DatasheetHuman LRRFIP1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant LRRFIP1 based upon sequence from Human
Isoform: Isoform 3
Host: QP6321 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) LRRFIP1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6321.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details). of Isoform 3
Expression Region: Met1 – Arg314
Amino Acid Sequence: MTSPAAAQSR EIDCLSPEAQ KLAEARLAAK RAARAEAREI RMKELERQQK EVEERPEKDF TEKGSRNMPG LSAATLASLG GTSSRRGSGD TSISIDTEAS IREIKDSLAE VEEKYKKAMV SNAQLDNEKT NFMYQVDTLK DMLLELEEQL AESRRQYEEK NKEFEREKHA HSILQFQFAE VKEALKQREE MLEKHGIILN SEIATNGETS DTLNNVGYQG PTKMTKEELN ALKSTGDGTL GRASEVEVKN EIVANVGKRE ILHNTEKEQH TEDTVKDCVD IEVFPAGENT EDQKSSEDTA PFLGTLAGAT YEEQSLSTCS LDR
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human LRRFIP1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human LRRFIP1 Protein General Information | |
|---|---|
| Alternate Names | |
| GCF2, FLIIAP1, GCF-2, HUFI-1, FLAP-1, TRIP, FLAP1, Leucine-rich repeat flightless-interacting protein | |
| Molecular Weight | |
| Isoform 3 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | LRRFIP1 |
| Entrez Gene ID | 9208 |
| Ensemble Gene ID | ENSG00000124831 |
| RefSeq Protein Accession(s) | NP_001131022.1 |
| RefSeq mRNA Accession(s) | NM_001137550.1, NM_001137552.1, NM_001137553.1, NM_004735.3 |
| UniProt ID(s) | Q32MZ4 |
| UniGene ID(s) | Hs.471779 |
| HGNC ID(s) | HGNC:6702 |
| COSMIC ID Link(s) | LRRFIP1 |
| KEGG Gene ID(s) | hsa:9208 |
| PharmGKB ID(s) | PA30465 |
| General Description of Recombinant Human LRRFIP1 Protein. | |
| Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5′-AGCCCCCGGCG-3′) and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.