PDF DatasheetHuman Mitogen-activated protein kinase 6 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Mitogen-activated protein kinase 6 based upon sequence from Human
Host: QP6341 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Mitogen-activated protein kinase 6, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6341.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Asn721
Amino Acid Sequence: MAEKFESLMN IHGFDLGSRY MDLKPLGCGG NGLVFSAVDN DCDKRVAIKK IVLTDPQSVK HALREIKIIR RLDHDNIVKV FEILGPSGSQ LTDDVGSLTE LNSVYIVQEY METDLANVLE QGPLLEEHAR LFMYQLLRGL KYIHSANVLH RDLKPANLFI NTEDLVLKIG DFGLARIMDP HYSHKGHLSE GLVTKWYRSP RLLLSPNNYT KAIDMWAAGC IFAEMLTGKT LFAGAHELEQ MQLILESIPV VHEEDRQELL SVIPVYIRND MTEPHKPLTQ LLPGISREAL DFLEQILTFS PMDRLTAEEA LSHPYMSIYS FPMDEPISSH PFHIEDEVDD ILLMDETHSH IYNWERYHDC QFSEHDWPVH NNFDIDEVQL DPRALSDVTD EEEVQVDPRK YLDGDREKYL EDPAFDTNYS TEPCWQYSDH HENKYCDLEC SHTCNYKTRS SSYLDNLVWR ESEVNHYYEP KLIIDLSNWK EQSKEKSDKK GKSKCERNGL VKAQIALEEA SQQLAGKERE KNQGFDFDSF IAGTIQLSSQ HEPTDVVDKL NDLNSSVSQL ELKSLISKSV SQEKQEKGMA NLAQLEALYQ SSWDSQFVSG GEDCFFINQF CEVRKDEQVE KENTYTSYLD KFFSRKEDTE MLETEPVEDG KLGERGHEEG FLNNSGEFLF NKQLESIGIP QFHSPVGSPL KSIQATLTPS AMKSSPQIPH QTYSSILKHL N
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Mitogen-activated protein kinase 6 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Mitogen-activated protein kinase 6 Protein General Information | |
|---|---|
| Alternate Names | |
| ERK3, PRKM6, p97MAPK, HsT17250 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | MAPK6 |
| Entrez Gene ID | 5597 |
| Ensemble Gene ID | ENSG00000069956 |
| RefSeq Protein Accession(s) | NP_002739.1 |
| RefSeq mRNA Accession(s) | NM_002748.3, XM_005254537.2, XM_005254538.2, XM_005254539.3, XM_011521782.1 |
| UniProt ID(s) | Q16659 |
| UniGene ID(s) | Hs.411847 |
| HGNC ID(s) | HGNC:6879 |
| COSMIC ID Link(s) | MAPK6 |
| KEGG Gene ID(s) | hsa:5597 |
| PharmGKB ID(s) | PA30624 |
| General Description of Recombinant Human Mitogen-activated protein kinase 6 Protein. | |
| Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.