PDF DatasheetRat MAPT / Tau Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant MAPT / Tau based upon sequence from Rat
Host: QP6345 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Rattus norvegicus (Rat) MAPT / Tau, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6345.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala2 – Leu752
Amino Acid Sequence: AEPRQEFDTM EDQAGDYTML QDQEGDMDHG LKESPPQPPA DDGSEEPGSE TSDAKSTPTA EDVTAPLVEE RAPDKQATAQ SHTEIPEGTT AEEAGIGDTP NMEDQAAGHV TQEPQKVEIF SQSLLVEPGR REGQAPDSGI SDWTHQQVPS MSGAPLPPQG LREATHQPLG TRPEDVERSH PASELLWQES PQKEAWGKDR LGSEEEVDED ITMDESSQES PPSQASLAPG TATPQARSVS ASGVSGETTS IPGFPAEGSI PLPADFFSKV SAETQASPPE GPGTGPSEEG HEAAPEFTFH VEIKASAPKE QDLEGATVVG APAEEQKARG PSVGKGTKEA SLLEPTDKQP AAGLPGRPVS RVPQLKARVA GVSKDRTGND EKKAKTSTPS CAKTPSNRPC LSPTRPTPGS SDPLIKPSSP AVCPEPATSP KYVSSVTPRN GSPGTKQMKL KGADGKTGAK IATPRGAATP GQKGTSNATR IPAKTTPSPK TPPGSGEPPK SGERSGYSSP GSPGTPGSRS RTPSLPTPPT REPKKVAVVR TPPKSPSASK SRLQTAPVPM PDLKNVRSKI GSTENLKHQP GGGKVQIINK KLDLSNVQSK CGSKDNIKHV PGGGSVHIVY KPVDLSKVTS KCGSLGNIHH KPGGGQVEVK SEKLDFKDRV QSKIGSLDNI THVPGGGNKK IETHKLTFRE NAKAKTDHGA EIVYKSPVVS GDTSPRHLSN VSSTGSIDMV DSPQLATLAD EVSASLAKQG L
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Rat MAPT / Tau Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Rat MAPT / Tau Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Mapt |
| UniProt ID(s) | P19332 |
| UniGene ID(s) | Rn.2455 |
| COSMIC ID Link(s) | Mapt |
| General Description of Recombinant Rat MAPT / Tau Protein. | |
| Promotes microtubule assbly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma mbrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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