PDF DatasheetHuman Homeobox protein MOX-1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Homeobox protein MOX-1 based upon sequence from Human
Host: QP6354 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Homeobox protein MOX-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6354.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Glu254
Amino Acid Sequence: MDPAASSCMR SLQPPAPVWG CLRNPHSEGN GASGLPHYPP TPFSFHQKPD FLATATAAYP DFSASCLAAT PHSLPQEEHI FTEQHPAFPQ SPNWHFPVSD ARRRPNSGPA GGSKEMGTSS LGLVDTTGGP GDDYGVLGST ANETEKKSSR RRKESSDNQE NRGKPEGSSK ARKERTAFTK EQLRELEAEF AHHNYLTRLR RYEIAVNLDL SERQVKVWFQ NRRMKWKRVK GGQPISPNGQ DPEDGDSTAS PSSE
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Homeobox protein MOX-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Homeobox protein MOX-1 Protein General Information | |
|---|---|
| Alternate Names | |
| MOX1, KFS2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | MEOX1 |
| Entrez Gene ID | 4222 |
| Ensemble Gene ID | ENSG00000005102 |
| RefSeq Protein Accession(s) | NP_001035091.1 |
| RefSeq mRNA Accession(s) | NM_001040002.1, NM_004527.3, NM_013999.3 |
| UniProt ID(s) | P50221 |
| UniGene ID(s) | Hs.438 |
| HGNC ID(s) | HGNC:7013 |
| COSMIC ID Link(s) | MEOX1 |
| KEGG Gene ID(s) | hsa:4222 |
| PharmGKB ID(s) | PA30747 |
| General Description of Recombinant Human Homeobox protein MOX-1 Protein. | |
| Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints. Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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