PDF DatasheetHuman MFG-E8 / lactadherin Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant MFG-E8 / lactadherin based upon sequence from Human
Host: QP6356 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) MFG-E8 / lactadherin, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6356.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Leu24 – Cys387
Amino Acid Sequence: LDICSKNPCH NGGLCEEISQ EVRGDVFPSY TCTCLKGYAG NHCETKCVEP LGMENGNIAN SQIAASSVRV TFLGLQHWVP ELARLNRAGM VNAWTPSSND DNPWIQVNLL RRMWVTGVVT QGASRLASHE YLKAFKVAYS LNGHEFDFIH DVNKKHKEFV GNWNKNAVHV NLFETPVEAQ YVRLYPTSCH TACTLRFELL GCELNGCANP LGLKNNSIPD KQITASSSYK TWGLHLFSWN PSYARLDKQG NFNAWVAGSY GNDQWLQVDL GSSKEVTGII TQGARNFGSV QFVASYKVAY SNDSANWTEY QDPRTGSSKI FPGNWDNHSH KKNLFETPIL ARYVRILPVA WHNRIALRLE LLGC
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human MFG-E8 / lactadherin Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human MFG-E8 / lactadherin Protein General Information | |
|---|---|
| Alternate Names | |
| MFG-E8, lactadherin, HsT19888, OAcGD3S, SED1, SPAG10, EDIL1, HMFG, MFG-E8, hP47, BA46, MFGM | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | MFGE8 |
| Entrez Gene ID | 4240 |
| Ensemble Gene ID | ENSG00000140545 |
| RefSeq Protein Accession(s) | NP_001108086.1 |
| RefSeq mRNA Accession(s) | NM_001114614.2, NM_001310319.1, NM_001310320.1, NM_001310321.1, NM_005928.3 |
| UniProt ID(s) | Q08431 |
| UniGene ID(s) | Hs.3745 |
| HGNC ID(s) | HGNC:7036 |
| COSMIC ID Link(s) | MFGE8 |
| KEGG Gene ID(s) | hsa:4240 |
| PharmGKB ID(s) | PA30772 |
| General Description of Recombinant Human MFG-E8 / lactadherin Protein. | |
| Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization . Contributes to phagocytic roval of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication.1 Publication | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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