PDF DatasheetHuman Methylenetetrahydrofolate reductase Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Methylenetetrahydrofolate reductase based upon sequence from Human
Host: QP6391 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Methylenetetrahydrofolate reductase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6391.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Pro656
Amino Acid Sequence: MVNEARGNSS LNPCLEGSAS SGSESSKDSS RCSTPGLDPE RHERLREKMR RRLESGDKWF SLEFFPPRTA EGAVNLISRF DRMAAGGPLY IDVTWHPAGD PGSDKETSSM MIASTAVNYC GLETILHMTC CRQRLEEITG HLHKAKQLGL KNIMALRGDP IGDQWEEEEG GFNYAVDLVK HIRSEFGDYF DICVAGYPKG HPEAGSFEAD LKHLKEKVSA GADFIITQLF FEADTFFRFV KACTDMGITC PIVPGIFPIQ GYHSLRQLVK LSKLEVPQEI KDVIEPIKDN DAAIRNYGIE LAVSLCQELL ASGLVPGLHF YTLNREMATT EVLKRLGMWT EDPRRPLPWA LSAHPKRREE DVRPIFWASR PKSYIYRTQE WDEFPNGRWG NSSSPAFGEL KDYYLFYLKS KSPKEELLKM WGEELTSEES VFEVFVLYLS GEPNRNGHKV TCLPWNDEPL AAETSLLKEE LLRVNRQGIL TINSQPNING KPSSDPIVGW GPSGGYVFQK AYLEFFTSRE TAEALLQVLK KYELRVNYHL VNVKGENITN APELQPNAVT WGIFPGREII QPTVVDPVSF MFWKDEAFAL WIERWGKLYE EESPSRTIIQ YIHDNYFLVN LVDNDFPLDN CLWQVVEDTL ELLNRPTQNA RETEAP
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Methylenetetrahydrofolate reductase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Methylenetetrahydrofolate reductase Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | MTHFR |
| Entrez Gene ID | 4524 |
| Ensemble Gene ID | ENSG00000177000 |
| RefSeq Protein Accession(s) | NP_001317287.1 |
| RefSeq mRNA Accession(s) | NM_001330358.1, NM_005957.4, XM_005263460.4, XM_005263462.4 |
| UniProt ID(s) | P42898 |
| UniGene ID(s) | Hs.214142 |
| HGNC ID(s) | HGNC:7436 |
| COSMIC ID Link(s) | MTHFR |
| KEGG Gene ID(s) | hsa:4524 |
| PharmGKB ID(s) | PA245 |
| General Description of Recombinant Human Methylenetetrahydrofolate reductase Protein. | |
| Catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine rethylation to methionine. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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