PDF DatasheetHuman 5-formyltetrahydrofolate cyclo-ligase Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant 5-formyltetrahydrofolate cyclo-ligase based upon sequence from Human
Host: QP6392 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) 5-formyltetrahydrofolate cyclo-ligase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6392.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala2 – Ala203
Amino Acid Sequence: AAAAVSSAKR SLRGELKQRL RAMSAEERLR QSRVLSQKVI AHSEYQKSKR ISIFLSMQDE IETEEIIKDI FQRGKICFIP RYRFQSNHMD MVRIESPEEI SLLPKTSWNI PQPGEGDVRE EALSTGGLDL IFMPGLGFDK HGNRLGRGKG YYDAYLKRCL QHQEVKPYTL ALAFKEQICL QVPVNENDMK VDEVLYEDSS TA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human 5-formyltetrahydrofolate cyclo-ligase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human 5-formyltetrahydrofolate cyclo-ligase Protein General Information | |
|---|---|
| Alternate Names | |
| HsT19268 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | MTHFS |
| Entrez Gene ID | 10588 |
| Ensemble Gene ID | ENSG00000136371 |
| RefSeq Protein Accession(s) | NP_001186687.1 |
| RefSeq mRNA Accession(s) | NM_001199758.1, NM_006441.3 |
| UniProt ID(s) | P49914 |
| UniGene ID(s) | Hs.194294 |
| HGNC ID(s) | HGNC:7437 |
| COSMIC ID Link(s) | MTHFS |
| KEGG Gene ID(s) | hsa:10588 |
| PharmGKB ID(s) | PA31239 |
| General Description of Recombinant Human 5-formyltetrahydrofolate cyclo-ligase Protein. | |
| Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10-methenyltetrahydrofolate. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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