PDF DatasheetHuman Cytoplasmic protein NCK2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Cytoplasmic protein NCK2 based upon sequence from Human
Host: QP6408 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Cytoplasmic protein NCK2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6408.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Gln380
Amino Acid Sequence: MTEEVIVIAK WDYTAQQDQE LDIKKNERLW LLDDSKTWWR VRNAANRTGY VPSNYVERKN SLKKGSLVKN LKDTLGLGKT RRKTSARDAS PTPSTDAEYP ANGSGADRIY DLNIPAFVKF AYVAEREDEL SLVKGSRVTV MEKCSDGWWR GSYNGQIGWF PSNYVLEEVD EAAAESPSFL SLRKGASLSN GQGSRVLHVV QTLYPFSSVT EEELNFEKGE TMEVIEKPEN DPEWWKCKNA RGQVGLVPKN YVVVLSDGPA LHPAHAPQIS YTGPSSSGRF AGREWYYGNV TRHQAECALN ERGVEGDFLI RDSESSPSDF SVSLKASGKN KHFKVQLVDN VYCIGQRRFH TMDELVEHYK KAPIFTSEHG EKLYLVRALQ
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Cytoplasmic protein NCK2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Cytoplasmic protein NCK2 Protein General Information | |
|---|---|
| Alternate Names | |
| NCKbeta, GRB4 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | NCK2 |
| Entrez Gene ID | 8440 |
| Ensemble Gene ID | ENSG00000071051 |
| RefSeq Protein Accession(s) | NP_001004720.1 |
| RefSeq mRNA Accession(s) | NM_001004720.2, NM_003581.4, XM_006712797.3, XM_011511991.2, XM_017005103.1, XM_017005104.1, XM_017005105.1 |
| UniProt ID(s) | O43639 |
| UniGene ID(s) | Hs.529244 |
| HGNC ID(s) | HGNC:7665 |
| COSMIC ID Link(s) | NCK2 |
| KEGG Gene ID(s) | hsa:8440 |
| PharmGKB ID(s) | PA31467 |
| General Description of Recombinant Human Cytoplasmic protein NCK2 Protein. | |
| Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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