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Human Nephrin Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Nephrin based upon sequence from Human
Host: QP6429 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Nephrin, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6429.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Gln23 – Ala257
Amino Acid Sequence: QLAIPASVPR GFWALPENLT VVEGASVELR CGVSTPGSAV QWAKDGLLLG PDPRIPGFPR YRLEGDPARG EFHLHIEACD LSDDAEYECQ VGRSEMGPEL VSPRVILSIL VPPKLLLLTP EAGTMVTWVA GQEYVVNCVS GDAKPAPDIT ILLSGQTISD ISANVNEGSQ QKLFTVEATA RVTPRSSDNR QLLVCEASSP ALEAPIKASF TVNVLFPPGP PVIEWPGLDE GHVRA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Nephrin Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Nephrin Protein General Information | |
|---|---|
| Alternate Names | |
| nephrin, CNF, NPHN | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | NPHS1 |
| Entrez Gene ID | 4868 |
| Ensemble Gene ID | ENSG00000161270 |
| RefSeq Protein Accession(s) | NP_004637.1 |
| RefSeq mRNA Accession(s) | NM_004646.3 |
| UniProt ID(s) | O60500 |
| UniGene ID(s) | Hs.122186 |
| HGNC ID(s) | HGNC:7908 |
| COSMIC ID Link(s) | NPHS1 |
| KEGG Gene ID(s) | hsa:4868 |
| PharmGKB ID(s) | PA31709 |
| General Description of Recombinant Human Nephrin Protein. | |
| Ses to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
