PDF DatasheetHuman Pro-neuregulin-2, membrane-bound isoform Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Pro-neuregulin-2, membrane-bound isoform based upon sequence from Human
Host: QP6436 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Pro-neuregulin-2, membrane-bound isoform, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6436.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Cys112 – Arg405
Amino Acid Sequence: CYSPSLKSVQ DQAYKAPVVV EGKVQGLVPA GGSSSNSTRE PPASGRVALV KVLDKWPLRS GGLQREQVIS VGSCVPLERN QRYIFFLEPT EQPLVFKTAF APLDTNGKNL KKEVGKILCT DCATRPKLKK MKSQTGQVGE KQSLKCEAAA GNPQPSYRWF KDGKELNRSR DIRIKYGNGR KNSRLQFNKV KVEDAGEYVC EAENILGKDT VRGRLYVNSV STTLSSWSGH ARKCNETAKS YCVNGGVCYY IEGINQLSCK CPNGFFGQRC LEKLPLRLYM PDPKQKAEEL YQKR
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Pro-neuregulin-2, membrane-bound isoform Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Pro-neuregulin-2, membrane-bound isoform Protein General Information | |
|---|---|
| Alternate Names | |
| DON1, HRG2, NTAK | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | NRG2 |
| Entrez Gene ID | 9542 |
| Ensemble Gene ID | ENSG00000158458 |
| RefSeq Protein Accession(s) | NP_001171864.1 |
| RefSeq mRNA Accession(s) | NM_001184935.1, NM_004883.2, NM_013981.3, NM_013982.2, NM_013983.2, XM_006714810.3 |
| UniProt ID(s) | O14511 |
| UniGene ID(s) | Hs.408515 |
| HGNC ID(s) | HGNC:7998 |
| COSMIC ID Link(s) | NRG2 |
| KEGG Gene ID(s) | hsa:9542 |
| PharmGKB ID(s) | PA31777 |
| General Description of Recombinant Human Pro-neuregulin-2, membrane-bound isoform Protein. | |
| Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. May also promote the heterodimerization with the EGF receptor. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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