PDF DatasheetHuman Nuclear pore complex protein Nup153 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Nuclear pore complex protein Nup153 based upon sequence from Human
Host: QP6439 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Nuclear pore complex protein Nup153, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6439.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Lys657 – Gly880
Amino Acid Sequence: KAGSSWQCDT CLLQNKVTDN KCIACQAAKL SPRDTAKQTG IETPNKSGKT TLSASGTGFG DKFKPVIGTW DCDTCLVQNK PEAIKCVACE TPKPGTCVKR ALTLTVVSES AETMTASSSS CTVTTGTLGF GDKFKRPIGS WECSVCCVSN NAEDNKCVSC MSEKPGSSVP ASSSSTVPVS LPSGGSLGLE KFKKPEGSWD CELCLVQNKA DSTKCLACES AKPG
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Nuclear pore complex protein Nup153 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Nuclear pore complex protein Nup153 Protein General Information | |
|---|---|
| Alternate Names | |
| N153, HNUP153 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | NUP153 |
| Entrez Gene ID | 9972 |
| Ensemble Gene ID | ENSG00000124789 |
| RefSeq Protein Accession(s) | NP_001265138.1 |
| RefSeq mRNA Accession(s) | NM_001278209.1, NM_001278210.1, NM_005124.3 |
| UniProt ID(s) | P49790 |
| UniGene ID(s) | Hs.601591 |
| HGNC ID(s) | HGNC:8062 |
| COSMIC ID Link(s) | NUP153 |
| KEGG Gene ID(s) | hsa:9972 |
| PharmGKB ID(s) | PA31848 |
| General Description of Recombinant Human Nuclear pore complex protein Nup153 Protein. | |
| Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding elent in the nuclear phase of the NPC essential for normal nucleoCytoplasmic domain transport of proteins and mRNAs. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with TPR, regulates the nuclear export of unspliced mRNA species bearing constitutive transport elent (CTE) in a NXF1- and KHDRBS1-independent manner. Mediates TPR anchoring to the nuclear mbrane at NPC. The repeat-containing domain may be involved in anchoring other components of the NPC to the pore mbrane. Possible DNA-binding subunit of the nuclear pore complex (NPC). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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