PDF DatasheetHuman 2-oxoglutarate dehydrogenase, mitochondrial Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant 2-oxoglutarate dehydrogenase, mitochondrial based upon sequence from Human
Isoform: Isoform 3
Host: QP6447 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) 2-oxoglutarate dehydrogenase, mitochondrial, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6447.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details). of Isoform 3
Expression Region: Ser41 – Phe423
Amino Acid Sequence: SAPVAAEPFL SGTSSNYVEE MYCAWLENPK SVHKSWDIFF RNTNAGAPPG TAYQSPLPLS RGSLAAVAHA QSLVEAQPNV DKLVEDHLAV QSLIRAYQIR GHHVAQLDPL GILDADLDSS VPADIISSTD KLGFYGLDES DLDKVFHLPT TTFIGGQESA LPLREIIRRL EMAYCQHIGV EFMFINDLEQ CQWIRQKFET PGIMQFTNEE KRTLLARLVR STRFEEFLQR KWSSEKRFGL EGCEVLIPAL KTIIDKSSEN GVDYVIMGMP HRGRLNVLAN VIRKELEQIF CQFDSKLEAA DEGSGDVKYH LGMYHRRINR VTDRNITLSL VANPSHLEAA DPVVMGKTKA EQFYCGDTEG KKVRPRERRA RQIVKAPCSS MEF
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human 2-oxoglutarate dehydrogenase, mitochondrial Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human 2-oxoglutarate dehydrogenase, mitochondrial Protein General Information | |
|---|---|
| Alternate Names | |
| AKGDH, E1k, OGDC | |
| Molecular Weight | |
| Isoform 3 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | OGDH |
| Entrez Gene ID | 4967 |
| Ensemble Gene ID | ENSG00000105953 |
| RefSeq Protein Accession(s) | NP_001003941.1 |
| RefSeq mRNA Accession(s) | NM_001003941.2, NM_001165036.1, NM_002541.3 |
| UniProt ID(s) | Q02218 |
| UniGene ID(s) | Hs.488181 |
| HGNC ID(s) | HGNC:8124 |
| COSMIC ID Link(s) | OGDH |
| KEGG Gene ID(s) | hsa:4967 |
| PharmGKB ID(s) | PA31910 |
| General Description of Recombinant Human 2-oxoglutarate dehydrogenase, mitochondrial Protein. | |
| The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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