PDF DatasheetHuman N-glycosylase / DNA lyase Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant N-glycosylase / DNA lyase based upon sequence from Human
Host: QP6448 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) N-glycosylase/DNA lyase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6448.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Gly345
Amino Acid Sequence: MPARALLPRR MGHRTLASTP ALWASIPCPR SELRLDLVLP SGQSFRWREQ SPAHWSGVLA DQVWTLTQTE EQLHCTVYRG DKSQASRPTP DELEAVRKYF QLDVTLAQLY HHWGSVDSHF QEVAQKFQGV RLLRQDPIEC LFSFICSSNN NIARITGMVE RLCQAFGPRL IQLDDVTYHG FPSLQALAGP EVEAHLRKLG LGYRARYVSA SARAILEEQG GLAWLQQLRE SSYEEAHKAL CILPGVGTKV ADCICLMALD KPQAVPVDVH MWHIAQRDYS WHPTTSQAKG PSPQTNKELG NFFRSLWGPY AGWAQAVLFS ADLRQSRHAQ EPPAKRRKGS KGPEG
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human N-glycosylase / DNA lyase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human N-glycosylase / DNA lyase Protein General Information | |
|---|---|
| Alternate Names | |
| MUTM, OGH1, HMMH, HOGG1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | OGG1 |
| Entrez Gene ID | 4968 |
| Ensemble Gene ID | ENSG00000114026 |
| RefSeq Protein Accession(s) | NP_002533.1 |
| RefSeq mRNA Accession(s) | NM_002542.5, NM_016819.3, NM_016820.3, NM_016821.2, NM_016826.2, NM_016827.2, NM_016828.2, NM_016829.2 |
| UniProt ID(s) | O15527 |
| UniGene ID(s) | Hs.380271 |
| HGNC ID(s) | HGNC:8125 |
| COSMIC ID Link(s) | OGG1 |
| KEGG Gene ID(s) | hsa:4968 |
| PharmGKB ID(s) | PA31912 |
| General Description of Recombinant Human N-glycosylase / DNA lyase Protein. | |
| DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3′ to the lesion. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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