PDF DatasheetHuman Origin recognition complex subunit 4 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Origin recognition complex subunit 4 based upon sequence from Human
Host: QP6453 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Origin recognition complex subunit 4, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6453.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Leu436
Amino Acid Sequence: MSSRKSKSNS LIHTECLSQV QRILRERFCR QSPHSNLFGV QVQYKHLSEL LKRTALHGES NSVLIIGPRG SGKTMLINHA LKELMEIEEV SENVLQVHLN GLLQINDKIA LKEITRQLNL ENVVGDKVFG SFAENLSFLL EALKKGDRTS SCPVIFILDE FDLFAHHKNQ TLLYNLFDIS QSAQTPIAVI GLTCRLDILE LLEKRVKSRF SHRQIHLMNS FGFPQYVKIF KEQLSLPAEF PDKVFAEKWN ENVQYLSEDR SVQEVLQKHF NISKNLRSLH MLLMLALNRV TASHPFMTAV DLMEASQLCS MDSKANIVHG LSVLEICLII AMKHLNDIYE EEPFNFQMVY NEFQKFVQRK AHSVYNFEKP VVMKAFEHLQ QLELIKPMER TSGNSQREYQ LMKLLLDNTQ IMNALQKYPN CPTDVRQWAT SSLSWL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Origin recognition complex subunit 4 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Origin recognition complex subunit 4 Protein General Information | |
|---|---|
| Alternate Names | |
| ORC4P, ORC4L | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ORC4 |
| Entrez Gene ID | 5000 |
| Ensemble Gene ID | ENSG00000115947 |
| RefSeq Protein Accession(s) | NP_001177808.1 |
| RefSeq mRNA Accession(s) | NM_001190879.2, NM_001190881.2, NM_001190882.2, NM_002552.4, NM_181741.3, NM_181742.3, XM_011511255.2, XM_017004226.1, XM_017004227.1 |
| UniProt ID(s) | O43929 |
| UniGene ID(s) | Hs.558364 |
| HGNC ID(s) | HGNC:8490 |
| COSMIC ID Link(s) | ORC4 |
| KEGG Gene ID(s) | hsa:5000 |
| PharmGKB ID(s) | PA32811 |
| General Description of Recombinant Human Origin recognition complex subunit 4 Protein. | |
| Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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