PDF DatasheetHuman PIGF / PLGF Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant PIGF / PLGF based upon sequence from Human
Host: QP6485 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) PIGF / PLGF, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6485.
Bioactivity Data: Untested
Full Length? Full Length of Isoform PlGF-2
Expression Region: Leu19 – Arg170
Amino Acid Sequence: LPAVPPQQWA LSAGNGSSEV EVVPFQEVWG RSYCRALERL VDVVSEYPSE VEHMFSPSCV SLLRCTGCCG DENLHCVPVE TANVTMQLLK IRSGDRPSYV ELTFSQHVRC ECRPLREKMK PERCGDAVPR R
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human PIGF / PLGF Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human PIGF / PLGF Protein General Information | |
|---|---|
| Alternate Names | |
| PIGF, PLGF, PIGF, SHGC-10760, PGFL, PLGF, PlGF-2, D12S1900 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PGF |
| Entrez Gene ID | 5228 |
| Ensemble Gene ID | ENSG00000119630 |
| RefSeq Protein Accession(s) | NP_001193941.1 |
| RefSeq mRNA Accession(s) | NM_001207012.1, NM_002632.5 |
| UniProt ID(s) | P49763 |
| UniGene ID(s) | Hs.252820 |
| HGNC ID(s) | HGNC:8893 |
| COSMIC ID Link(s) | PGF |
| KEGG Gene ID(s) | hsa:5228 |
| PharmGKB ID(s) | PA33231 |
| General Description of Recombinant Human PIGF / PLGF Protein. | |
| Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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