PDF DatasheetHuman PLTP Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant PLTP based upon sequence from Human
Host: QP6507 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) PLTP, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6507.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Glu18 – Val493
Amino Acid Sequence: EFPGCKIRVT SKALELVKQE GLRFLEQELE TITIPDLRGK EGHFYYNISE VKVTELQLTS SELDFQPQQE LMLQITNASL GLRFRRQLLY WFFYDGGYIN ASAEGVSIRT GLELSRDPAG RMKVSNVSCQ ASVSRMHAAF GGTFKKVYDF LSTFITSGMR FLLNQQICPV LYHAGTVLLN SLLDTVPVRS SVDELVGIDY SLMKDPVAST SNLDMDFRGA FFPLTERNWS LPNRAVEPQL QEEERMVYVA FSEFFFDSAM ESYFRAGALQ LLLVGDKVPH DLDMLLRATY FGSIVLLSPA VIDSPLKLEL RVLAPPRCTI KPSGTTISVT ASVTIALVPP DQPEVQLSSM TMDARLSAKM ALRGKALRTQ LDLRRFRIYS NHSALESLAL IPLQAPLKTM LQIGVMPMLN ERTWRGVQIP LPEGINFVHE VVTNHAGFLT IGADLHFAKG LREVIEKNRP ADVRASTAPT PSTAAV
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human PLTP Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human PLTP Protein General Information | |
|---|---|
| Alternate Names | |
| PLTP, HDLCQ9, BPIFE | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PLTP |
| Entrez Gene ID | 5360 |
| Ensemble Gene ID | ENSG00000100979 |
| RefSeq Protein Accession(s) | NP_001229849.1 |
| RefSeq mRNA Accession(s) | NM_001242920.1, NM_001242921.1, NM_006227.3, NM_182676.2 |
| UniProt ID(s) | P55058 |
| UniGene ID(s) | Hs.439312 |
| HGNC ID(s) | HGNC:9093 |
| COSMIC ID Link(s) | PLTP |
| KEGG Gene ID(s) | hsa:5360 |
| PharmGKB ID(s) | PA273 |
| General Description of Recombinant Human PLTP Protein. | |
| Facilitates the transfer of a spectrum of different lipid molecules, including diacylglycerol, phosphatidic acid, sphingomyelin, phosphatidylcholine, phosphatidylglycerol, cerebroside and phosphatidyl ethanolamine. Essential for the transfer of excess surface lipids from triglyceride-rich lipoproteins to HDL, thereby facilitating the formation of smaller lipoprotein rnants, contributing to the formation of LDL, and assisting in the maturation of HDL particles. PLTP also plays a key role in the uptake of cholesterol from peripheral cells and tissues that is subsequently transported to the liver for degradation and excretion. Two distinct forms of PLTP exist in plasma: an active form that can transfer PC from phospholipid vesicles to high-density lipoproteins (HDL), and an inactive form that lacks this capability. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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