PDF DatasheetHuman Serum paraoxonase / arylesterase 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Serum paraoxonase / arylesterase 1 based upon sequence from Human
Host: QP6513 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Serum paraoxonase/arylesterase 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6513.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala2 – Leu355
Amino Acid Sequence: AKLIALTLLG MGLALFRNHQ SSYQTRLNAL REVQPVELPN CNLVKGIETG SEDLEILPNG LAFISSGLKY PGIKSFNPNS PGKILLMDLN EEDPTVLELG ITGSKFDVSS FNPHGISTFT DEDNAMYLLV VNHPDAKSTV ELFKFQEEEK SLLHLKTIRH KLLPNLNDIV AVGPEHFYGT NDHYFLDPYL QSWEMYLGLA WSYVVYYSPS EVRVVAEGFD FANGINISPD GKYVYIAELL AHKIHVYEKH ANWTLTPLKS LDFNTLVDNI SVDPETGDLW VGCHPNGMKI FFYDSENPPA SEVLRIQNIL TEEPKVTQVY AENGTVLQGS TVASVYKGKL LIGTVFHKAL YCEL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Serum paraoxonase / arylesterase 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Serum paraoxonase / arylesterase 1 Protein General Information | |
|---|---|
| Alternate Names | |
| ESA, PON, MVCD5 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PON1 |
| Entrez Gene ID | 5444 |
| Ensemble Gene ID | ENSG00000005421 |
| RefSeq Protein Accession(s) | NP_000437.3 |
| RefSeq mRNA Accession(s) | NM_000446.5 |
| UniProt ID(s) | P27169 |
| UniGene ID(s) | Hs.370995 |
| HGNC ID(s) | HGNC:9204 |
| COSMIC ID Link(s) | PON1 |
| KEGG Gene ID(s) | hsa:5444 |
| PharmGKB ID(s) | PA33529 |
| General Description of Recombinant Human Serum paraoxonase / arylesterase 1 Protein. | |
| Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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