PDF DatasheetHuman POU domain, class 5, transcription factor 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant POU domain, class 5, transcription factor 1 based upon sequence from Human
Host: QP6517 protein expressed in E. coli.
Tag: His-B2M
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) POU domain, class 5, transcription factor 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6517.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Asn360
Amino Acid Sequence: MAGHLASDFA FSPPPGGGGD GPGGPEPGWV DPRTWLSFQG PPGGPGIGPG VGPGSEVWGI PPCPPPYEFC GGMAYCGPQV GVGLVPQGGL ETSQPEGEAG VGVESNSDGA SPEPCTVTPG AVKLEKEKLE QNPEESQDIK ALQKELEQFA KLLKQKRITL GYTQADVGLT LGVLFGKVFS QTTICRFEAL QLSFKNMCKL RPLLQKWVEE ADNNENLQEI CKAETLVQAR KRKRTSIENR VRGNLENLFL QCPKPTLQQI SHIAQQLGLE KDVVRVWFCN RRQKGKRSSS DYAQREDFEA AGSPFSGGPV SFPLAPGPHF GTPGYGSPHF TALYSSVPFP EGEAFPPVSV TTLGSPMHSN
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human POU domain, class 5, transcription factor 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human POU domain, class 5, transcription factor 1 Protein General Information | |
|---|---|
| Alternate Names | |
| OCT4, OCT3, OTF3, Oct-3, OTF-3, OTF4, Oct-4 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | POU5F1 |
| Entrez Gene ID | 5460 |
| Ensemble Gene ID | ENSG00000204531 |
| RefSeq Protein Accession(s) | NP_001272916.1 |
| RefSeq mRNA Accession(s) | NM_001285987.1, NM_002701.5 |
| UniProt ID(s) | Q01860 |
| UniGene ID(s) | Hs.249184 |
| HGNC ID(s) | HGNC:9221 |
| COSMIC ID Link(s) | POU5F1 |
| KEGG Gene ID(s) | hsa:5460 |
| PharmGKB ID(s) | PA33545 |
| General Description of Recombinant Human POU domain, class 5, transcription factor 1 Protein. | |
| Transcription factor that binds to the octamer motif (5′-ATTTGCAT-3′). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.