PDF DatasheetMouse Perforin-1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Perforin-1 based upon sequence from Mouse
Host: QP6526 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Perforin-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6526.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Pro21 – Trp554
Amino Acid Sequence: PCYTATRSEC KQKHKFVPGV WMAGEGMDVT TLRRSGSFPV NTQRFLRPDR TCTLCKNSLM RDATQRLPVA ITHWRPHSSH CQRNVAAAKV HSTEGVAREA AANINNDWRV GLDVNPRPEA NMRASVAGSH SKVANFAAEK TYQDQYNFNS DTVECRMYSF RLVQKPPLHL DFKKALRALP RNFNSSTEHA YHRLISSYGT HFITAVDLGG RISVLTALRT CQLTLNGLTA DEVGDCLNVE AQVSIGAQAS VSSEYKACEE KKKQHKMATS FHQTYRERHV EVLGGPLDST HDLLFGNQAT PEQFSTWTAS LPSNPGLVDY SLEPLHTLLE EQNPKREALR QAISHYIMSR ARWQNCSRPC RSGQHKSSHD SCQCECQDSK VTNQDCCPRQ RGLAHLVVSN FRAEHLWGDY TTATDAYLKV FFGGQEFRTG VVWNNNNPRW TDKMDFENVL LSTGGPLRVQ VWDADYGWDD DLLGSCDRSP HSGFHEVTCE LNHGRVKFSY HAKCLPHLTG GTCLEYAPQG LLGDPPGNRS GAVW
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse Perforin-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse Perforin-1 Protein General Information | |
|---|---|
| Alternate Names | |
| Pfn, Pfp, Prf-1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Prf1 |
| Entrez Gene ID | 18646 |
| Ensemble Gene ID | ENSMUSG00000037202 |
| RefSeq Protein Accession(s) | NP_035203.3 |
| RefSeq mRNA Accession(s) | NM_011073.3, XM_006513370.3 |
| UniProt ID(s) | P10820 |
| UniGene ID(s) | Mm.240313 |
| COSMIC ID Link(s) | Prf1 |
| KEGG Gene ID(s) | mmu:18646 |
| General Description of Recombinant Mouse Perforin-1 Protein. | |
| Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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