PDF DatasheetHuman PC4 and SFRS1-interacting protein Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant PC4 and SFRS1-interacting protein based upon sequence from Human
Host: QP6542 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) PC4 and SFRS1-interacting protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6542.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Asn530
Amino Acid Sequence: MTRDFKPGDL IFAKMKGYPH WPARVDEVPD GAVKPPTNKL PIFFFGTHET AFLGPKDIFP YSENKEKYGK PNKRKGFNEG LWEIDNNPKV KFSSQQAATK QSNASSDVEV EEKETSVSKE DTDHEEKASN EDVTKAVDIT TPKAARRGRK RKAEKQVETE EAGVVTTATA SVNLKVSPKR GRPAATEVKI PKPRGRPKMV KQPCPSESDI ITEEDKSKKK GQEEKQPKKQ PKKDEEGQKE EDKPRKEPDK KEGKKEVESK RKNLAKTGVT STSDSEEEGD DQEGEKKRKG GRNFQTAHRR NMLKGQHEKE AADRKRKQEE QMETEQQNKD EGKKPEVKKV EKKRETSMDS RLQRIHAEIK NSLKIDNLDV NRCIEALDEL ASLQVTMQQA QKHTEMITTL KKIRRFKVSQ VIMEKSTMLY NKFKNMFLVG EGDSVITQVL NKSLAEQRQH EEANKTKDQG KKGPNKKLEK EQTGSKTLNG GSDAQDGNQP QHNGESNEDS KDNHEASTKK KPSSEERETE ISLKDSTLDN
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human PC4 and SFRS1-interacting protein Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human PC4 and SFRS1-interacting protein Protein General Information | |
|---|---|
| Alternate Names | |
| PSIP2, p52, DFS70, LEDGF, p75, PAIP | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PSIP1 |
| Entrez Gene ID | 11168 |
| Ensemble Gene ID | ENSG00000164985 |
| RefSeq Protein Accession(s) | NP_001121689.1 |
| RefSeq mRNA Accession(s) | NM_001128217.2, NM_001317898.1, NM_001317900.1, NM_021144.3, NM_033222.4 |
| UniProt ID(s) | O75475 |
| UniGene ID(s) | Hs.658434 |
| HGNC ID(s) | HGNC:9527 |
| COSMIC ID Link(s) | PSIP1 |
| KEGG Gene ID(s) | hsa:11168 |
| PharmGKB ID(s) | PA33872 |
| General Description of Recombinant Human PC4 and SFRS1-interacting protein Protein. | |
| Transcriptional coactivator involved in neuroepithelial st cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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