PDF DatasheetHuman PTGDS / L-PGDS Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant PTGDS / L-PGDS based upon sequence from Human
Host: QP6550 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) PTGDS / L-PGDS, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6550.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala23 – Gln190
Amino Acid Sequence: APEAQVSVQP NFQQDKFLGR WFSAGLASNS SWLREKKAAL SMCKSVVAPA TDGGLNLTST FLRKNQCETR TMLLQPAGSL GSYSYRSPHW GSTYSVSVVE TDYDQYALLY SQGSKGPGED FRMATLYSRT QTPRAELKEK FTAFCKAQGF TEDTIVFLPQ TDKCMTEQ
Purity: Greater than 86% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human PTGDS / L-PGDS Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human PTGDS / L-PGDS Protein General Information | |
|---|---|
| Alternate Names | |
| PTGDS, L-PGDS, PGD2, PGDS, Ptgs3, 21kDa, L-PGDS, PGDS2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PTGDS |
| Entrez Gene ID | 5730 |
| Ensemble Gene ID | ENSG00000107317 |
| RefSeq Protein Accession(s) | NP_000945.3 |
| RefSeq mRNA Accession(s) | NM_000954.5 |
| UniProt ID(s) | P41222 |
| UniGene ID(s) | Hs.446429 |
| HGNC ID(s) | HGNC:9592 |
| COSMIC ID Link(s) | PTGDS |
| KEGG Gene ID(s) | hsa:5730 |
| PharmGKB ID(s) | PA33945 |
| General Description of Recombinant Human PTGDS / L-PGDS Protein. | |
| Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NR sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous syst and male reproductive syst. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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