PDF DatasheetHuman PTPRZ1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant PTPRZ1 based upon sequence from Human
Host: QP6557 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) PTPRZ1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6557.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ile36 – Tyr300
Amino Acid Sequence: IGWSYTGALN QKNWGKKYPT CNSPKQSPIN IDEDLTQVNV NLKKLKFQGW DKTSLENTFI HNTGKTVEIN LTNDYRVSGG VSEMVFKASK ITFHWGKCNM SSDGSEHSLE GQKFPLEMQI YCFDADRFSS FEEAVKGKGK LRALSILFEV GTEENLDFKA IIDGVESVSR FGKQAALDPF ILLNLLPNST DKYYIYNGSL TSPPCTDTVD WIVFKDTVSI SESQLAVFCE VLTMQQSGYV MLMDYLQNNF REQQYKFSRQ VFSSY
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human PTPRZ1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human PTPRZ1 Protein General Information | |
|---|---|
| Alternate Names | |
| RPTPB, HPTPzeta, PTPZ, R-PTP-zeta-2, PTP-ZETA, HPTPZ, PTP18, PTPRZ, RPTPbeta, phosphacan, Receptor-type tyrosine-protein phosphatase ze | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PTPRZ1 |
| Entrez Gene ID | 5803 |
| Ensemble Gene ID | ENSG00000106278 |
| RefSeq Protein Accession(s) | NP_001193767.1 |
| RefSeq mRNA Accession(s) | NM_001206838.1, NM_001206839.1, NM_002851.2, XM_005250519.1 |
| UniProt ID(s) | P23471 |
| UniGene ID(s) | Hs.489824 |
| HGNC ID(s) | HGNC:9685 |
| COSMIC ID Link(s) | PTPRZ1 |
| KEGG Gene ID(s) | hsa:5803 |
| PharmGKB ID(s) | PA34029 |
| General Description of Recombinant Human PTPRZ1 Protein. | |
| Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the bryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual mory, probably via the dephosphorylation of proteins that are part of important signaling cascades . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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