PDF DatasheetHuman Ras-related protein Rab-5A Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Ras-related protein Rab-5A based upon sequence from Human
Host: QP6571 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Ras-related protein Rab-5A, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6571.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Asn215
Amino Acid Sequence: MASRGATRPN GPNTGNKICQ FKLVLLGESA VGKSSLVLRF VKGQFHEFQE STIGAAFLTQ TVCLDDTTVK FEIWDTAGQE RYHSLAPMYY RGAQAAIVVY DITNEESFAR AKNWVKELQR QASPNIVIAL SGNKADLANK RAVDFQEAQS YADDNSLLFM ETSAKTSMNV NEIFMAIAKK LPKNEPQNPG ANSARGRGVD LTEPTQPTRN QCCSN
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Ras-related protein Rab-5A Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Ras-related protein Rab-5A Protein General Information | |
|---|---|
| Alternate Names | |
| RAB5 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | RAB5A |
| Entrez Gene ID | 5868 |
| Ensemble Gene ID | ENSG00000144566 |
| RefSeq Protein Accession(s) | NP_001278977.1 |
| RefSeq mRNA Accession(s) | NM_001292048.1, NM_004162.4 |
| UniProt ID(s) | P20339 |
| UniGene ID(s) | Hs.475663 |
| HGNC ID(s) | HGNC:9783 |
| COSMIC ID Link(s) | RAB5A |
| KEGG Gene ID(s) | hsa:5868 |
| PharmGKB ID(s) | PA34143 |
| General Description of Recombinant Human Ras-related protein Rab-5A Protein. | |
| The small GTPases Rab are key regulators of intracellular mbrane trafficking, from the formation of transport vesicles to their fusion with mbranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to mbranes different sets of downstream effectors directly responsible for vesicle formation, movent, tethering and fusion. RAB5A is required for the fusion of plasma mbranes and early endosomes. Contributes to the regulation of filopodia extension. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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