PDF DatasheetHuman Ras-related protein Ral-B Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Ras-related protein Ral-B based upon sequence from Human
Host: QP6582 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Ras-related protein Ral-B, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6582.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Cys206
Amino Acid Sequence: MAANKSKGQS SLALHKVIMV GSGGVGKSAL TLQFMYDEFV EDYEPTKADS YRKKVVLDGE EVQIDILDTA GQEDYAAIRD NYFRSGEGFL LVFSITEHES FTATAEFREQ ILRVKAEEDK IPLLVVGNKS DLEERRQVPV EEARSKAEEW GVQYVETSAK TRANVDKVFF DLMREIRTKK MSENKDKNGK KSSKNKKSFK ERC
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Ras-related protein Ral-B Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Ras-related protein Ral-B Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | RALB |
| Entrez Gene ID | 5899 |
| Ensemble Gene ID | ENSG00000144118 |
| RefSeq Protein Accession(s) | NP_002872.1 |
| RefSeq mRNA Accession(s) | NM_002881.2, XM_005263724.1, XM_005263727.1, XM_005263728.1, XM_005263729.2, XM_017004622.1 |
| UniProt ID(s) | P11234 |
| UniGene ID(s) | Hs.469820 |
| HGNC ID(s) | HGNC:9840 |
| COSMIC ID Link(s) | RALB |
| KEGG Gene ID(s) | hsa:5899 |
| PharmGKB ID(s) | PA34198 |
| General Description of Recombinant Human Ras-related protein Ral-B Protein. | |
| Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells. Plays a role in the late stages of cytokinesis and is required for the abscission of the bridge joining the sister cells emerging from mitosis. Required for suppression of apoptosis. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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