Human REG3A / HIP Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant REG3A / HIP based upon sequence from Human
Host: QP6593 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) REG3A / HIP, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6593.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Glu27 – Asp175
Amino Acid Sequence: EEPQRELPSA RIRCPKGSKA YGSHCYALFL SPKSWTDADL ACQKRPSGNL VSVLSGAEGS FVSSLVKSIG NSYSYVWIGL HDPTQGTEPN GEGWEWSSSD VMNYFAWERN PSTISSPGHC ASLSRSTAFL RWKDYNCNVR LPYVCKFTD
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human REG3A / HIP Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
Recombinant Human REG3A / HIP Protein General Information | |
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Alternate Names | |
REG3A, HIP, HIP/PAP, REG-III, PAP, HIP, INGAP, PAP1, PAP-H, REG3, PBCGF | |
Curated Database and Bioinformatic Data | |
Gene Symbol | REG3A |
Entrez Gene ID | 5068 |
Ensemble Gene ID | ENSG00000172016 |
RefSeq Protein Accession(s) | NP_002571.1 |
RefSeq mRNA Accession(s) | NM_002580.2, NM_138937.2, NM_138938.2 |
UniProt ID(s) | Q06141 |
UniGene ID(s) | Hs.567312 |
HGNC ID(s) | HGNC:8601 |
COSMIC ID Link(s) | REG3A |
KEGG Gene ID(s) | hsa:5068 |
PharmGKB ID(s) | PA32931 |
General Description of Recombinant Human REG3A / HIP Protein. | |
Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway. |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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