PDF DatasheetHuman Reelin Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Reelin based upon sequence from Human
Host: QP6597 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Reelin, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6597.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ala26 – Thr254
Amino Acid Sequence: AAGYYPRFSP FFFLCTHHGE LEGDGEQGEV LISLHIAGNP TYYVPGQEYH VTISTSTFFD GLLVTGLYTS TSVQASQSIG GSSAFGFGIM SDHQFGNQFM CSVVASHVSH LPTTNLSFIW IAPPAGTGCV NFMATATHRG QVIFKDALAQ QLCEQGAPTD VTVHPHLAEI HSDSIILRDD FDSYHQLQLN PNIWVECNNC ETGEQCGAIM HGNAVTFCEP YGPRELITT
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Reelin Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Reelin Protein General Information | |
|---|---|
| Alternate Names | |
| RL, ETL7, LIS2, PRO1598 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | RELN |
| Entrez Gene ID | 5649 |
| Ensemble Gene ID | ENSG00000189056 |
| RefSeq Protein Accession(s) | NP_005036.2 |
| RefSeq mRNA Accession(s) | NM_005045.3, NM_173054.2 |
| UniProt ID(s) | P78509 |
| UniGene ID(s) | Hs.655654 |
| HGNC ID(s) | HGNC:9957 |
| COSMIC ID Link(s) | RELN |
| KEGG Gene ID(s) | hsa:5649 |
| PharmGKB ID(s) | PA34323 |
| General Description of Recombinant Human Reelin Protein. | |
| Extracellular domain matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it ses to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the Extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.