PDF DatasheetHuman Regulator of G-protein signaling 10 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Regulator of G-protein signaling 10 based upon sequence from Human
Isoform: Isoform 3
Host: QP6602 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Regulator of G-protein signaling 10, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6602.
Bioactivity Data: Untested
Full Length? Full Length of Isoform 3
Expression Region: Met1 – Thr181
Amino Acid Sequence: MFNRAVSRLS RKRPPSDIHD SDGSSSSSHQ SLKSTAKWAA SLENLLEDPE GVKRFREFLK KEFSEENVLF WLACEDFKKM QDKTQMQEKA KEIYMTFLSS KASSQVNVEG QSRLNEKILE EPHPLMFQKL QDQIFNLMKY DSYSRFLKSD LFLKHKRTEE EEEDLPDAQT AAKRASRIYN T
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Regulator of G-protein signaling 10 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Regulator of G-protein signaling 10 Protein General Information | |
|---|---|
| Molecular Weight | |
| Isoform 3 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | RGS10 |
| Entrez Gene ID | 6001 |
| Ensemble Gene ID | ENSG00000148908 |
| RefSeq Protein Accession(s) | NP_001005339.1 |
| RefSeq mRNA Accession(s) | NM_001005339.1, NM_002925.3 |
| UniProt ID(s) | O43665 |
| UniGene ID(s) | Hs.501200 |
| HGNC ID(s) | HGNC:9992 |
| COSMIC ID Link(s) | RGS10 |
| KEGG Gene ID(s) | hsa:6001 |
| PharmGKB ID(s) | PA34362 |
| General Description of Recombinant Human Regulator of G-protein signaling 10 Protein. | |
| Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Modulates the activity of potassium channels that are activated in response to CHRM2 signaling. Activity on GNAZ is inhibited by palmitoylation of the G-protein | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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