PDF DatasheetHuman Regulator of G-protein signaling 7 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Regulator of G-protein signaling 7 based upon sequence from Human
Isoform: Isoform 5
Host: QP6606 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Regulator of G-protein signaling 7, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6606.
Bioactivity Data: Untested
Full Length? Full Length of Isoform 5
Expression Region: Met1 – Tyr487
Amino Acid Sequence: MAQGNNYGQT SNGVADESPN MLVYRKMEDV IARMQDEKNG IPIRTVKSFL SKIPSVFSGS DIVQWLIKNL TIEDPVEALH LGTLMAAHGY FFPISDHVLT LKDDGTFYRF QTPYFWPSNC WEPENTDYAV YLCKRTMQNK ARLELADYEA ESLARLQRAF ARKWEFIFMQ AEAQAKVDKK RDKIERKILD SQERAFWDVH RPVPGCVNTT EVDIKKSSRM RNPHKTRKSV YGLQNDIRSH SPTHTPTPET KPPTEDELQQ QIKYWQIQLD RHRLKMSKVA DSLLSYTEQY LEYDPFLLPP DPSNPWLSDD TTFWELEASK EPSQQRVKRW GFGMDEALKD PVGREQFLKF LESEFSSENL RFWLAVEDLK KRPIKEVPSR VQEIWQEFLA PGAPSAINLD SKSYDKTTQN VKEPGRYTFE DAQEHIYKLM KSDSYPRFIR SSAYQELLQA KKKSGNSMDR RTSFEKFAQN VGKSLTSKRL TSLAQSY
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Regulator of G-protein signaling 7 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Regulator of G-protein signaling 7 Protein General Information | |
|---|---|
| Molecular Weight | |
| Isoform 5 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | RGS7 |
| Entrez Gene ID | 6000 |
| Ensemble Gene ID | ENSG00000182901 |
| RefSeq Protein Accession(s) | NP_001269702.1 |
| RefSeq mRNA Accession(s) | NM_001282773.1, NM_001282775.1, NM_001282778.1, NM_002924.5, XM_005273218.3 |
| UniProt ID(s) | P49802 |
| UniGene ID(s) | Hs.655739 |
| HGNC ID(s) | HGNC:10003 |
| COSMIC ID Link(s) | RGS7 |
| KEGG Gene ID(s) | hsa:6000 |
| PharmGKB ID(s) | PA34378 |
| General Description of Recombinant Human Regulator of G-protein signaling 7 Protein. | |
| Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving th into their inactive GDP-bound form. Activity on G(o)-alpha is specifically enhanced by the RGS6/GNG5 dimer. May play a role in synaptic vesicle exocytosis. May play important role in the rapid regulation of neuronal excitability and the cellular responses to short-lived stimulations . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.