PDF DatasheetHuman Probable E3 SUMO-protein ligase RNF212 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Probable E3 SUMO-protein ligase RNF212 based upon sequence from Human
Host: QP6612 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Probable E3 SUMO-protein ligase RNF212, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6612.
Bioactivity Data: Untested
Full Length? Full Length
Amino Acid Sequence: MANWVFCNRC FQPPHRTSCF SLTNCGHVYC DACLGKGKKN ECLICKAPCR TVLLSKHTDA DIQAFFMSID SLCKKYSRET SQILEFQEKH RKRLLAFYRE KISRLEESLR KSVLQIEQLQ SMRSSQQTAF STIKSSVSTK PHGCLLPPHS SAPDRLESME VDLSPSPIRK SEIAAGPARI SMISPPQDGR MGPHLTASFC FIPWLTLSKP PVPGECVISR GSPCFCIDVC PHWLLLLAFS SGRHGELTNS KTLPIYAEVQ RAVLFPFQQA EGTLDTFRTP AVSVVFPLCQ FERKKSF
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Probable E3 SUMO-protein ligase RNF212 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Probable E3 SUMO-protein ligase RNF212 Protein General Information | |
|---|---|
| Alternate Names | |
| ZHP3 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | RNF212 |
| Entrez Gene ID | 285498 |
| Ensemble Gene ID | ENSG00000178222 |
| RefSeq Protein Accession(s) | NP_001124506.1 |
| RefSeq mRNA Accession(s) | NM_001131034.3, NM_001193318.2, NM_194439.4 |
| UniProt ID(s) | Q495C1 |
| UniGene ID(s) | Hs.248290 |
| HGNC ID(s) | HGNC:27729 |
| COSMIC ID Link(s) | RNF212 |
| KEGG Gene ID(s) | hsa:285498 |
| PharmGKB ID(s) | PA162401656 |
| General Description of Recombinant Human Probable E3 SUMO-protein ligase RNF212 Protein. | |
| SUMO E3 ligase that acts as a regulator of crossing-over during meiosis: required to couple chromosome synapsis to the formation of crossover-specific recombination complexes. Localizes to recombination sites and stabilizes meiosis-specific recombination factors, such as MutS-gamma complex proteins (MSH4 and MSH5) and TEX11. May mediate sumoylation of target proteins MSH4 and/or MSH5, leading to enhance their binding to recombination sites. Acts as a limiting factor for crossover designation and/or reinforcement and plays an antagonist role with CCNB1IP1/HEI10 in the regulation of meiotic recombination | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.